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Shanghai Yijing Pharmaceutical&Chemical Co.,Ltd
Shanghai Yijing Pharmaceutical&Chemical Co.,Ltd

China Pramiracetam for Brain Health Raw Nootropics Powder with Competitive Price manufacturer

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Pramiracetam for Brain Health Raw Nootropics Powder with Competitive Price 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram 
Place of Origin: Shanghai, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: Discreet packages
Brand Name: Yijing
Purity: 99%
Leading Time: About 4~8 working days
Reship Policy: About 60% Reship
Usages: Pharmaceutical Intermediate...
Skype: steroidglobal
Production Capacity: 500kg/month
Delivery Date: About 4~8 working days
CAS No.: 63547-13-7
Delivery Time: Within 24 hours
Payment Terms: T/T,MG,WU,Bitcoin
Certificates: ISO9001,KOSHER
MOQ: 10g
Whatsapp: +86 18918454969

Powder Nootropics Fladrafinil
Intellgence Development
Factory Supply
Pramiracetam for Brain Health
Competitive Price
Increased concentrations

CAS:63547-13-7
MF:C15H15NO3S
Molecular Weight:289.35
Appearance:White powder
Other Name:Acetamide,2-[(diphenylmethyl)sulfinyl]-N-hydroxy
Molecular Weight:289.35

Adrafinil is a synthetic nootropic compound. It is a prodrug for modafinil, meaning supplementation of adrafinil leads to increased concentrations of modafinil in the body.

Adrafinil supplementation increases alertness and wakefulness. Adrafinil is a stimulant, but it does not cause hyperactivity. Instead, it fights sleepiness.

Taking adrafinil may also improve memory, but further research is needed to confirm this effect.

Adrafinil works vicariously through modafinil. Further research is needed to determine the exact mechanisms of modafinil, but preliminary evidence suggests histaminergic signaling may play a vital role.

Safety information on adrafinil is lacking because modafinil is often used instead, for treatment of narcolepsy and excessive daytime sleepiness. Long term supplementation of adrafinil is not advised, since adrafinil is metabolized into modafinil in the liver, and there is no available evidence regarding liver safety. Adrafinil and modafinil are banned by the World Anti-Doping Agency (WADA) as a nonspecific stimulant compound.


How to Take

The standard dosage for adrafinil is reported to be 600-1,200mg, which for the purpose of treating narcolepsy was either 600mg twice daily (morning and midday) or 600-900mg taken once daily upon waking. Adrafinil is no longer used for this purpose due to modafinil being a more suitable pharmaceutical, and these doses reflect the recommendations for the prescription drug Olmifon when it was available.

Adrafinil should not be taken in the afternoon and evening, since supplementation would impair sleep. Adrafinil tends to be taken three times a week, for no longer than five months.

Sources

Adrafinil ({diphenylmethyl}sulfinyl-2 acetohydroxamic acid), sold until recently under the brand name of Olmifon, is a prodrug of the stimulant Modafinil and synthetic substance not found in any dietary source. Due to a lack of purported amphetamine-like stimulatory effects, adrafinil is classified as a eugregoric agent (an agent who promotes wakefulness and alertfulness). 

Adrafinil is sometimes used as a stimulatory agent in athletes[2] despite being considered a banned substance for competitive sports. The World Anti-Doping Agency (WADA) currently has adrafinil on its banned substances list, classifying it as a "non-specified stimulant". 

Benefits of Adrafinil

While there are undoubtedly differences, much of the research for adrafinil come from modafinil studies. Numerous studies show that modafinil is a powerful stimulant and wakefulness agent that is comparable in effects, but lacking in side effects with amphetamine based drugs like Adderall.

Although most people discuss adrafinil benefits in terms of the focus and concentration enhancement, there are others. Namely, the drug can improve short-term memory and reaction time in people who are sleep-deprived. This is one of the reasons the drug is considered a "wakefulness agent" as opposed to a stimulant. The properties are different than most stimulants though there are similar characteristics.

Another benefit of adrafinil is the mood altering aspect of the drug. While the drug is able to increase general subjective well being and mood it does not do so in a habit forming way like Adderall and other amphetamine based drugs.

Given that many children are using amphetamine based drugs daily and have problems related to withdrawal in adulthood, it is important to note the potential replacement therapy of modafinil and adrafinil compared to amphetamine-based prescription drugs.

Though adrafinil was originally developed for its eugeroic or wakefulness-promoting properties, it has been shown to produce significant cognitive benefits as well. For people who experience life-disrupting daytime fatigue because of shift work or sleep disorders like insomnia and sleep apnea, adrafinil can promote the physical and mental energy needed for an active life. It can also improve mental clarity, focus, and retention, making it a favorite with students.

Adrafinil has been shown to be a very effective general stimulant, preventing daytime sleepiness and dramatically increasing both energy and attentiveness without the hyperactivity and jitteriness commonly associated with stimulants. In fact, many users report a heightened sense of well-being, a reduction of stress, and general enhancement of pleasure – effects that may be attributable in large part to adrafinil's stimulation of dopamine receptors.

However, general stimulant effects are only part of Adrafinil's benefits. In addition to promoting wakefulness and increasing energy, adrafinil is strongly associated with a number of nootropic effects, including increased learning capacity, better memory, and faster recall. Users have reported that adrafinil improves their ability to focus and maintain concentration, enhances mental clarity, and makes it easier to do mentally taxing work over a long period of time.

Adrafinil Dosage

Adrafinil is converted into modafinil in the liver, which means some of the substance is lost in the process. The adrafinil dosage is in the 300 – 900 mg range. When the drug was used as a treatment for narcolepsy, doses were around 600 mg twice a day.

The adrafinil dosage is considerably higher than armodafinil (150 mg) and modafinil (200 mg) because so much of the drug is lost in metabolism. While the adrafinil dosage may depend highly upon the individual, you can bet it will be higher in the case of this smart drug compared to the other that are in the family.

Because the drug interacts with liver enzymes, it is recommended to take this drug no more than three times per week and no longer than 5 months at a time.

Finally, if you buy adrafinil, it is best to have a scale for measurement. Any milligram scale should provide an accurate measure. It is unsafe to form an adrafinil dosage based on "eyeballing" alone. Getting the dose wrong with adrafinil can come with side effects quickly so do not make this mistake when dosing.

Without a scale, many vendors provide a small red scoop. This small red spoon is approximately 10 – 15 mg so you can measure the adrafinil dosage that way.

HOW IT WORKS

Adrafinil acts on the adrenergic system, the part of the nervous system that releases adrenaline. Typically thought of in terms of the "fight or flight" response, a rapid release of adrenaline boosts energy and increases alertness. While not all of adrafinil's actions are completely understood, it is believed to replicate the positive effect of an adrenaline release by boosting adrenergic neurotransmitters.

Technically, adrafinil is a synthetic prodrug or precursor, which means that is initially pharmacologically inactive but is converted to an active form inside the body, through a normal metabolic process. Adrafinil is metabolized in the liver, where it is converted to Modafinil, a USFDA-approved treatment for wakefulness disorders sold under the brand names Alertec, Modavigil, and Provigil. The pharmacological effects of adrafinil are virtually identical to those of Modafinil.

Though the exact chemical mechanisms of adrafinil are not entirely clear, researchers hypothesize that in its metabolized form it acts as an adrenergic receptor agonist. One of its primary actions is thought to be the increased production and release of the neurotransmitter hypocretin, which in turn can trigger the increased production of dopamine, histamine, and norepinephrine. All of these neurotransmitters and hormones are directly related to wakefulness and energy levels, which largely explains adrafinil's stimulant properties.

The powerful mood and cognitive effects of adrafinil are believed to be created by several actions, including the positive modulation of glutamate receptors and inhibiting the breakdown of glutamate. This can result in enhanced neuronal communication, which improves memory and focus and creates better general cognitive function.

Adrafinil is also believed to stimulate the release of serotonin, which enhances mood by helping to lessen anxiety. It may also inhibit the breakdown of dopamine, a neurotransmitter that plays an enormous role in the brain's reward and pleasure centers as well as emotional responses.

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skype Ms. Leslie@pharm-china.com
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Fax: 86-181-21080540
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Company Info

Shanghai Yijing Pharmaceutical&Chemical Co.,Ltd [China (Mainland)]


Business Type:Manufacturer
City: Shanghai
Province/State: Shanghai
Country/Region: China (Mainland)

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